BNIP3L CLIA Kit for Human(Homo sapiens) | EIAab.comBNIP3L CLIA Kit for Human(Homo sapiens)

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Index > Protein center > BNIP3L(Gene name) > Human

BNIP3L (Gene name),

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (Protein name ), BNI3L_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

BNIP3L(BNIP3A;BNIP3H;NIX);

Protein name:

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;

Alternative:

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A;Adenovirus E1B19K-binding protein B5;NIP3-like protein X(NIP3L);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Self-associates. Interacts with BNIP3 and STEAP3. Interacts with SPATA18/MIEAP. Interacts with human adenovirus-2 E1B 19 kDa protein.

Function:

Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. May function as a tumor suppressor.

Subcellular Location:

Nucleus envelope Endoplasmic reticulum Mitochondrion outer membrane Membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

219

Sequence:

50:

100:

150:

200:

219:

LGLGIYIGKR | LSTPSASTY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:665

Pfam:

PF06553

String:

O60238

UniGene:

Hs.131226

SMR:

O60238

STRING:

9606.ENSP00000370003

MIM:

605368

Uniprot:

O60238

FOR

ELISA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

E15459h

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96T

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ELISA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

E15459m

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96T

ELISA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

E15459b

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96T

CLIA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

U15459b

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MSDS:

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Packing:

96T

CLIA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

U15459h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

U15459m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

P15459Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Cat.:

P15459Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Monoclonal Antibody for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

Protein for Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3."
Matsushima M. , Fujiwara T. , Takahashi E. , Minaguchi T. , Eguchi Y. , Tsujimoto Y. , Suzumori K. , Nakamura Y.
Genes Chromosomes Cancer21:230-235(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"BNIP3a, a human homolog of pro-apoptotic protein BNIP3, promotes apoptosis and interacts with viral and cellular anti-apoptosis proteins."
Yasuda M. , Han J.-W. , Dionne C.A. , Boyd J.M. , Chinnadurai G.
Submitted (1998-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins."
Chen G. , Cizeau J. , Vande Velde C. , Park J.H. , Bozek G. , Bolton J. , Shi L. , Dubik D. , Greenberg A.
J. Biol. Chem.274:7-10(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Fetal liver.
4.

"A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region."
Ohi N. , Tokunaga A. , Tsunoda H. , Nakano K. , Haraguchi K. , Oda K. , Motoyama N. , Nakajima T.
Cell Death Differ.6:314-325(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;SELF-ASSOCIATION;INTERACTION WITH BNIP3 AND HUMAN ADENOVIRUS-2 E1B 19 KDA PROTEIN
5.

"The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation."
Aerbajinai W. , Giattina M. , Lee Y.T. , Raffeld M. , Miller J.L.
Blood102:712-717(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
6.

"A catalog of genes in the human dermal papilla cells as identified by expressed sequence tags."
Farooq M. , Kim M.K. , Kim Y.H. , Seo J.M. , Lee H.M. , Sohn M.Y. , Hwang S.Y. , Chung H.J. , Im S.U. , Jung E.J. , Kim J.C.
Submitted (2000-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Hair follicle dermal papilla.
7.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Brain.
8.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
9.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Kidney.
10.

"DNA sequence and analysis of human chromosome 8."
Nusbaum C. , Mikkelsen T.S. , Zody M.C. , Asakawa S. , Taudien S. , Garber M. , Kodira C.D. , Schueler M.G. , Shimizu A. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Allen N.R. , Anderson S. , Asakawa T. , more...
Nature439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Bone marrow.
tissue: Cervix.
12.

"The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase."
Passer B.J. , Nancy-Portebois V. , Amzallag N. , Prieur S. , Cans C. , Roborel de Climens A. , Fiucci G. , Bouvard V. , Tuynder M. , Susini L. , Morchoisne S. , Crible V. , Lespagnol A. , Dausset J. , Oren M. , Amson R. , Telerman A.
Proc. Natl. Acad. Sci. U.S.A.100:2284-2289(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STEAP3
13.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria."
Kitamura N. , Nakamura Y. , Miyamoto Y. , Miyamoto T. , Kabu K. , Yoshida M. , Futamura M. , Ichinose S. , Arakawa H.
PLoS ONE6:E16060-E16060(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SPATA18;SUBCELLULAR LOCATION

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